Pengantin Setan tells the story of Echa and Ariel, who have been married for three years. In their relatively young marriage, their relationship has become strained and cold. Echa feels more comfortable in her dreams, where she meets a handsome man who always makes her happy. However, without her realizing it, strange events in her dreams would begin to have a direct impact on reality. The man in Echa's dreams turns out to be an incarnation of Jin Dasim, who has a mission to destroy marriages, especially of women he wants to possess completely. As Echa and Ariel slowly try to reconcile, Jin Dasim starts attacking them both in the dream world and reality. Now, Echa and Ariel must find a way out by performing Ruqyah to save Echa from the dark bonds that haunt her.